It is an over-the-counter drug that relieves pain and reduced fevers. Following the previously listed procedure, we were able to accomplish both tasks. We found the mass of acetylsalicylic acid present by multiplying the number of moles by the molar mass of the substance. It is also found to be useful in diseases accompanied by pain, discomfort, and fever, for instance the common cold and other viral infections. Employment, Human resource management, Human resources 943 Words 4 Pages reduction reaction that require high temperature and pressure along with a metal catalyst and H2. We demonstrated our total sample mass from the data obtained in the procedure.
The principles of back-annotation will also be explored and how this can be used to examine performance limitations of specific. In order to start the synthesis of acetaminophen I did an acid-base reaction by adding concentrated hydrochloric acid to p-aminophenol. Calculation: Here limiting reagent is p-aminophenol; hence yield should be calculated from its amount taken. German chemist Felix Hoffmann synthesized what would become known as aspirin in 1899 while working for Bayer. The data obtained from this part of the experiment later aided in finding the theoretical value and percentage yield value.
Stathopulos Department of Sciences, Chemistry Faculty University of Waterloo Teaching Assistant: Aaron Chan Prepared by: Section 001 Vithurjan Satkunarasan 20495383 Lab Partner: Ken Xu Introduction The synthesis of Acetaminophen is based on the amine group of p-aminophenol being acetylated by acetic anhydride to form an amide functional group. This can be avoided in the future by waiting longer to make certain that the product is completely dry. Take a mp of your recrystallized acetaminophen lit mp 169-170. Lab 10 — Lab Report — Lab 10 Williamson Ether Synthesis Phenacetin from Acetaminophen Erica Li Lab. Moreover, the green method will not use any catalyst but using heating source instead microwave. The Merck Index, which is an encyclopedia of chemicals, drugs, and biologicals, lists the following information under acetaminophen: large monoclinic prisms from water, mp 169-170. In the 5th century B.
After it seemed that no more of the solid would dissolve, the flask was allowed to cool to room temperature. An inappreciable amount of material was collected, so although observations were made, nothing else could be done with the substance. The purpose of this experiment is to determine the melting points of the crude and purified form of acetaminophen using a MelTemp melting point apparatus. When crystallization ceases 15 minutes , collect the crystals as before, rinsing once with a few mL of cold water, and air drying. This compound is furthermore acidified producing salicylic acid, the precursor to aceytlsalicylic acid, aspirin. A small amount of material was placed in a melting-point tube and then the Mel-temp was used. Abstract Aspirin is the common name for the compound acetylsalicylic acid, widely used as a fever reducer and as a pain killer.
As the percent yield was 27. Acetaminophen, which can be synthesized from p-aminophenol, is probably best recognized under the trade name Tylenol. Aldous Huxley, Brave New World, Dystopia 776 Words 3 Pages Media Argument Synthesis A man stumbles out of a bar and digs through the junk in his pocket to find his keys. One of the reasons why the yield is below 100% is because there was a loss of product when during the transfer of product in the various steps. To recrystallize the product and characterize it by melting point analysis and nbsp; The Acetaminophen Molecule- Tylenol — World of Molecules in 1887. The second- year undergraduate students can perform the entire multistep synthesis.
Then I browsed other journals to look for other references that shall support my chosen topic. Kristyn Murphy Organic Chemistry I Laboratory Synthesis of Acetaminophen Introduction The purpose of this experiment was to synthesize an amide acetaminophen p-acetamidophenol p-acetamidophenol from an amine p-aminophenol p-aminophenol and an acid anhydride acetic anhydride. Only a few elements on the periodic table are nonmetals: C, N, O, S, Cl, and F. Another source of error in this experiment could have come in measuring the melting point of the acetaminophen. Based on the comparison of. The precipitated solution undergoes vacuum filtration where a white solid like substance remains. The product dissolved almost immediately as the acetic acid was added.
This lab was also intended to teach us how to isolate and recrystallize our compound in order to get rid of as much impurities as possible and check the purity using the melting points. A When 5mL of water is added for every 1g of crude product, there is a faster rate of recrystallization because the solvent is more saturated with the solute and therefore able to produce more product. In this process, methanol and oxygen. Prepare Buchner funnel with filter paper. Another reason why the yield is lower is because when the cooling and crystallized product in the Erlenmeyer flask is moved to do the vacuum filtration some of the solute is dissolved again and so will not be taken into account into the actual yield. Transfer one sample at a time into a 125mL Erlenmeyer flask. The hot solution of methanol and water was slowly added to the acetaminophen and sodium dithionite until most of the solid was dissolved.
This same Grignard reagent would then be used to prepare a tertiary alcohol and then purify and characterize the product. Using the theoretical yield and the actual yield the percentage yield of the reaction was determined at 59. Acetic acid, Acetic anhydride, Acetyl 973 Words 4 Pages Synthesis of Aspirin Learning Goals 1. Table of Collected And some Calculated Data Objective: To determine the purity of the synthesized aspirin. The solution was again poured into a Büchner funnel and the crystals were dried for 5 minutes. The flask was heated to 100°C on a hot plate. Acetic acid, Acetic anhydride, Acetyl 1228 Words 4 Pages Name Period Date The Synthesis of Aspirin Background Pharmaceutical research labs perform chemical reactions between organic molecules that contain mostly carbon.
This creates a mostly pure form of acetaminophen. In the field of Chemistry, an organic compound is any compound with carbon atoms in them. Clarify the solution by gravity filtration, if necessary. Further loss of product may have occurred elsewhere as well. The first part of the experiment aims to synthesize aspirin from the reaction of salicylic acid with acetic anhydride with the aid of phosphoric acid as a catalyst. Synthesis of Acetaminophen Lab Report Bijal Patel, 20467049 Partner: Poojan Parikh T. During the recrystallization the impure sample could have been extracted resulting in a low yield.